Searchable abstracts of presentations at key conferences in endocrinology

ea0020p135 | Thyroid | ECE2009

Evaluation of cyclins a and b1 expression in classical and nonclassical variants of papillary thyroid carcinoma

Naze M , Dedecjus M , Stasikowska O , Sporny S , Brzezinski J

The loss of regulatory control of the cell, leading to unrestrained cell proliferation, is a hallmark of cancer. In a number of cancers, over expression of cyclin A and cyclin B1 proteins has been reported and in some instances the level of expression correlated well with the grades of malignancy. In the present study, we analyzed, by immunohistochemistry, the expression of cyclins A and B1, proteins enable passing G(2)-restriction point, in different histological variants of ...